MINOTECH biotechnology is the in-house biotechnology production facility of the Institute of Molecular Biology and Biotechnology in Crete, Greece founded in 1986 by Prof. Vassilis Bouriotis. MINOTECH biotechnology remains the sole microbial biotechnology unit in Greece active in the production of Molecular Biology tools and is highlighted as one of the 16 international suppliers of Restriction Enzymes (REs) in the largest database on REs (REBASE, rebase.neb.com).

MINOTECH biotechnology has over 28 years of experience specialized in production of bacterial-derived proteins. We produce a wide array of high purity and superior quality Restriction Endonucleases, DNA Modifying Enzymes and Molecular Weight Markers that aim to meet the needs of scientists engaged in Research, the Biotechnology Industry and the Clinical Laboratory. Our products are cited in more than 200 peer-reviewed publications and are supplied to customers directly or under OEM agreements through major European, Asian and North American distributors.

The proprietary protein purification procedures developed at MINOTECH biotechnology and the thorough quality control (every batch is strictly tested) allow us to offer top quality products at the most competitive prices and fast delivery.

MINOTECH biotechnology facilities, products and services are certified with ISO 9001:2008 from TUV HELLAS.

An active R&D section has as a goal the extension of our product portfolio and the establishment of collaborations under Interdisciplinary research grants with the academia or industry.

The three main pillars of MINOTECH biotechnology future growth are:

Participation in research programs with partners from Academia or Industry. We are willing to collaborate in research programs that aim to identify enzymes with applications in Molecular biology and biotechnology. One of our main projects is the identification of enzymes from extremophilic microorganisms with biotechnological interest.

Training of Young Scientists. Since MINOTECH biotechnology is an active part of IMBB we offer the ideal environment for training students and young scientists in Molecular Biology and biotechnology methodologies. At the same time trainees will come in close contact with our production team giving them the opportunity to acquire knowledge on how a biotechnology unit functions and develops.

Expanding of OEM Agreements and distribution network. We focus towards the establishment of strategic partnerships with companies worldwide either for customized production of enzymes, bulk supply of our products or distribution of our items. Feel free to contact us for more details.

Our name is the combination of two terms Minoan civilization and technology.

Minotech biotechnology is based in Heraklion Crete. Between 3000 and 1100 BC Minoan civilization flourished in this area. Minoans were well known for their unique art, architecture and achievements in science that made a significant contribution to the development of Western European civilization as it is known today.

The Phaistos Disc

Phaistos Disc is a mysterious circular clay disc covered with inscribed symbols on both sides that are unlike any signs in any writing system. The disk is thought to date to the middle Minoan Bronze Age, in the second Millennium BC, and was discovered in 1908 at the palace of Phaistos, in Crete. While not really a printed work, some has labeled the Phaistos Disc as the ‘earliest typewritten work’ while other as the ‘first Minoan CD-ROM'.


Dimitris Kafetzopoulos
Head Scientist
Deputy Director of IMBB

PhD University of Crete

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Dimitris Kafetzopoulos

Dimitris is the Deputy Director of IMBB and supervises the productive units of IMBB (MINOTECH biotechnology, MINOTECH genomics). He is also leading Ancient DNA Laboratory that focuses on the analysis archeological biological samples through state-of the art DNA analysis techniques. His main research interests for more than ten years now, remain within the field of Post-Genomic analysis and in particular the molecular profiling of complex diseases and the elucidation of the mechanisms underlying them.


Dimitris Koutsioulis
Executive Director 

PhD, University of Crete

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Dimitris joined MINOTECH biotechnology in 2015. Previously he worked as a postdoctoral researcher in New England Biolabs and the University of Crete. His research focus is on the identification of novel enzymes from extreme environments (Antarctica, thermal vents, salt pits) and modification of enzymatic properties through protein engineering. He is responsible for commercial organization and R&D activities at MINOTECH biotechnology while he coordinates strategic partnerships with companies or academic institutions.

Core Activities

Support scientific community with high quality molecular biology products
Production of bacterial recombinant proteins tailored to customer's needs using our Fermentation facilities and state of the art protein purification systems
Participation in Research Grants and establishment of new partnerships aiming at the discovery of novel enzyme activities